High throughput drug screening technique is a new technique
for the drug
development.
The core part of this technology consists with in vitro or cell
level screening model, computer controlled working system and
ingenious biology reaction testing system.
Advancing and deepening the computer-aided drug screening technique,
we are developing an Integrated High-throughput screening Platform
(IHP). This platform includes drug screening in the molecule and
cell level. Molecular level screening is a process of using Gene
engineering method to produce drug-target protein, then with the
help of relevant biophysical technique to screen and valuate the
compounds. While, cellular screening is the process of using cellular
molecular biological technique to establish certain cell model
that can express drug-target protein and finally reach the goal
of screening and measuring the activities of compounds.
IHP system makes it available to screen the large number of
synthesized compounds and natural chemical products as well as
to evaluate the drug leads in their effectiveness, metabolism,
side and cytotoxic effects rapidly and comprehensively. We believe
that the IHP system will help greatly to the reduction of cost
and time in the discovery and development of new drugs.